Rat Angiopoietin-Related Protein 3 (ANGPTL3) ELISA Kit
585€ (96 tests)
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name
Rat Angiopoietin-Related Protein 3 (ANGPTL3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx574936
tested applications
ELISA
Description
Rat Angiopoietin-Related Protein 3 (ANGPTL3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Angiopoietin Like 3 concentrations in serum, plasma and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Angiopoietin-Related Protein 3 (ANGPTL3) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 62.5 pg/ml - 4000 pg/ml |
| Sensitivity | 37.5 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | F7FHP0 |
| Alias | ANG-5,ANGPT5,ANL3,FHBL2 |
| Background | Elisa kits for ANGPTL3 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ANGPTL3 is a secreted glycoprotein primarily expressed in the liver, where it plays a central role in regulating lipid metabolism. ANGPTL3 functions as an inhibitor of lipoprotein lipase (LPL) and endothelial lipase (EL), leading to increased plasma levels of triglycerides, cholesterol, and low-density lipoproteins (LDL). It is a key regulator of systemic energy homeostasis, influencing lipid storage and transport under fasting and fed conditions. Genetic loss-of-function mutations in ANGPTL3 are associated with familial combined hypolipidemia, a condition characterized by significantly reduced levels of triglycerides, LDL, and HDL cholesterol, highlighting its critical role in lipid metabolism. ANGPTL3 is also implicated in cardiovascular diseases, where elevated levels are linked to atherosclerosis and coronary artery disease due to lipid accumulation and vascular inflammation. In cancer, ANGPTL3 promotes tumor angiogenesis and metastasis by regulating endothelial cell proliferation and migration. Its role as a regulator of lipid metabolism and vascular biology makes ANGPTL3 a promising therapeutic target for treating hyperlipidemia, atherosclerosis, and related metabolic disorders.
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