Rat Alpha-1-Antiproteinase (SerpinA1) Protein
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935106861
info@markelab.com
Precio
312€ (20 µg)
Protein SERPINA1
proveedor
Abbexareference
abx692070Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat SerpinA1 Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat SERPINA1 (NP_071964.2) (Met1-Arg411) was expressed with a polyhistidine tag at the C-terminus.
Background
The SERPINA1 gene, commonly known as alpha-1 antitrypsin (A1AT), encodes a protein that plays a crucial role in protecting tissues from enzymes of inflammatory cells, particularly neutrophil elastase. This gene is part of the serine protease inhibitor (serpin) superfamily and is located on chromosome 14 (14q32.13). Alpha-1 antitrypsin is primarily synthesized in the liver, although it is also produced in smaller quantities by other tissues, including the lungs, intestines, and kidneys. The protein encoded by SERPINA1 is a glycoprotein that circulates in the blood and functions as a major inhibitor of proteases, especially neutrophil elastase, which, if left unchecked, can degrade elastin and other extracellular matrix components, leading to tissue damage.
Características del producto
category
Proteins and Peptides
origin
Rat
host
HEK293 cells
immunogen target
Alpha-1-Antiproteinase (SERPINA1)
host
HEK293 cells
form
tested applications
SDS-PAGE
size 1
20 µg
size 2
100 µg
observerd MW
Molecular Weight: 45.2 kDa Sequence Fragment: Met1-Arg411 Tag: C-terminal His tag Validity: The validity for this protein is 12 months.
expression
Recombinant
purity
> 95% (SDS-PAGE)
buffer
Prior to lyophilization: PBS, pH 7.4.
storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
or code
SERPINA1
dry ice
No
availability
Shipped within 5-15 working days.
alias
PI,A1A,AAT; PI1,A1AT,nNIF,PRO2275,alpha1AT,Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1
NCBI accession
NP_071964.2
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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