Rat Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) ELISA Kit

Este producto es parte de ALDH - Aldehyde dehydrogenase family member
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501496
tested applications
ELISA

Description

Rat Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Aldehyde dehydrogenase family 3 member B1 concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryELISA Kits
Immunogen TargetAldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1)
ReactivityRat
Detection MethodColorimetric
Assay DataQuantitative
Test Range0.156 ng/ml - 10 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
FormLyophilized
Tested ApplicationsELISA
Sample TypeTissue homogenates, cell lysates and other biological fluids.
AvailabilityShipped within 5-15 working days. The validity for this kit is 6 months.
StorageShipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDQ5XI42
AliasALDH3B1,ALDH7,Aldehyde dehydrogenase 7
BackgroundElisa kits for ALDH3B1
StatusRUO
NoteValidity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

ALDH3B1 is a cytosolic enzyme involved in the detoxification of reactive aldehydes generated from lipid peroxidation and environmental toxins. It is expressed in various tissues, including the liver, kidneys, and lungs, where it plays a protective role against oxidative stress and aldehyde-induced cellular damage. ALDH3B1 contributes to cellular homeostasis by metabolizing toxic aldehydes such as formaldehyde and 4-HNE, reducing protein and DNA adduct formation. Dysregulation of ALDH3B1 has been linked to metabolic and neurodegenerative disorders, where impaired aldehyde detoxification exacerbates oxidative damage. In cancer, ALDH3B1 has been identified as a tumor suppressor in certain contexts, as its activity reduces cellular oxidative stress and inhibits tumor progression. Recent studies suggest its involvement in maintaining redox balance and preventing aldehyde-associated toxicity in tissues exposed to oxidative or environmental stressors.

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