Rat Alcohol Dehydrogenase 3 (ADH3) CLIA Kit
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Description
Alcohol Dehydrogenase 3 Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Documents del producto
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Alcohol Dehydrogenase 3 (ADH3) |
| Reactivity | Rat |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.138 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma, tissue homogenates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | ADH1C,ADH3 |
| Background | CLIA Kits ADH1C |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADH1C encodes the gamma subunit of class I ADH enzymes, which functions alongside ADH1A and ADH1B in alcohol metabolism. It is highly expressed in the liver and stomach, contributing to the oxidation of ethanol and other alcohols. Genetic variants of ADH1C, such as ADH1C1 and ADH1C2, result in differing enzymatic activities, affecting alcohol elimination rates and acetaldehyde production. These differences are associated with variations in susceptibility to alcohol-related disorders, including liver disease, alcohol dependence, and cancer. In addition to ethanol metabolism, ADH1C plays a role in the processing of retinoids and steroids, highlighting its significance in cellular homeostasis and signaling. Dysregulation of ADH1C has been linked to increased acetaldehyde levels, contributing to oxidative stress and tissue damage, particularly in alcohol-related liver and gastric diseases. Its importance in metabolic and detoxification pathways makes it a critical enzyme in maintaining systemic balance.
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