Rat ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2 (ARFGEF2) ELISA Kit

Este producto es parte de ARFGEF - ADP ribosylation factor guanine nucleotide exchange factor
Rat ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2 (ARFGEF2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits ARFGEF2

proveedor

Abbexa

reference

abx503781

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2 (ARFGEF2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Brefeldin A-inhibited guanine nucleotide-exchange protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ADP ribosylation factor guanine nucleotide exchange factor 2 (ARFGEF2) is a guanine nucleotide exchange factor (GEF) that activates ADP-ribosylation factor (ARF) proteins, playing a key role in regulating cellular processes such as vesicular trafficking, actin cytoskeleton remodeling, and signal transduction ARFGEF2 promotes the exchange of GDP for GTP on ARF proteins, thus facilitating their activation and enabling the regulation of processes like vesicle formation, endocytosis, and the organization of cell membranes ARFGEF2 also regulates actin dynamics, contributing to cell migration, morphology, and division It plays a significant role in the immune system, where it influences immune cell trafficking and activation Dysregulation of ARFGEF2 has been associated with diseases such as cancer, where abnormal ARF and actin dynamics contribute to tumor cell migration and metastasis Additionally, ARFGEF2 is involved in the regulation of metabolic processes, and its dysfunction can lead to metabolic disorders, immune diseases, and cancer

Características del producto

category

ELISA Kits


immunogen target

ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2 (ARFGEF2)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

BIG2,PVNH2,Brefeldin A-inhibited GEP 2,Brefeldin A-inhibited guanine nucleotide-exchange protein 2


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

ARFGEF2


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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