Rat Adhesion Molecule With Ig Like Domain 2 (AMIGO2) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Adhesion Molecule With Ig Like Domain 2 (AMIGO2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx501629
tested applications
ELISA
Description
Rat Adhesion Molecule With Ig Like Domain 2 (AMIGO2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Amphoterin-induced protein 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Adhesion Molecule With Ig Like Domain 2 (AMIGO2) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q7TNJ4 |
| Alias | AMIGO2,ALI1,AMIGO-2,Alivin-1 |
| Background | Elisa kits for AMIGO2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AMIGO2, like AMIGO1, is a cell adhesion molecule that regulates cell migration, adhesion, and survival. It is expressed in various tissues, including the brain, heart, and vascular system, where it participates in developmental processes and cellular signaling. AMIGO2 plays a role in the maintenance of endothelial cell integrity and vascular remodeling, making it essential for blood vessel formation and repair. In the context of cancer, AMIGO2 is implicated in tumor angiogenesis and metastasis by promoting cell survival and migration through interactions with signaling pathways such as PI3K/AKT. Overexpression of AMIGO2 has been observed in cancers such as hepatocellular carcinoma and gastric cancer, where it contributes to tumor progression and resistance to apoptosis. AMIGO2 also supports neuronal survival under stress conditions, linking it to neuroprotection and repair mechanisms in the nervous system. Its role in both vascular biology and tumorigenesis makes AMIGO2 a potential therapeutic target.
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