Rat Adenylate Kinase 2 (AK2) Protein

Este producto es parte de AK - Adenylate kinase
Rat Adenylate Kinase 2 (AK2) Protein
234€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Rat Adenylate Kinase 2 (AK2) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx168882
Tested Applications
WB, SDS-PAGE

Description

Rat AK2 Protein is a recombinant Rat protein expressed in E. coli.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Adenylate Kinase 2 (AK2)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Leu64-Ser232
Tag: N-terminal His tag
Origin
Rat
Conjugation
Unconjugated
Observed MW
Calculated MW: 22.8 kDa
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
P29410
Alias
ADK2
Background
Protein AK2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Background

AK2 is localized in the mitochondrial intermembrane space and is primarily responsible for ATP production in hematopoietic cells. AK2 catalyzes the same ADP-to-ATP conversion as AK1 but in the mitochondrial compartment, essential for maintaining cellular energy supply. Mutations in AK2 are linked to reticular dysgenesis, a severe immunodeficiency caused by disrupted leukocyte differentiation. AK2 has critical functions in energy homeostasis during apoptosis, as ATP signaling is necessary for programmed cell death. Its role extends to regulating mitochondrial biogenesis and influencing mitochondrial DNA replication. The expression of AK2 is also vital in early embryonic development and immune system maintenance.

Productos relacionados

abx004999

Adenylate Kinase 2, Mitochondrial (AK2) Antibody

AK2 Antibody is a Rabbit Polyclonal antibody against AK2. Adenylate kinases are involved in regulating the adenine nucle…

Ver producto
abx033892

Adenylate Kinase 2, Mitochondrial (AK2) Antibody

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversib…

Ver producto
abx033893

Adenylate Kinase 2, Mitochondrial (AK2) Antibody

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversib…

Ver producto