Rat Adenylate Kinase 2 (AK2) Protein

Este producto es parte de AK - Adenylate kinase
Rat Adenylate Kinase 2 (AK2) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein AK2

proveedor

Abbexa

reference

abx168882

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat AK2 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

AK2 is localized in the mitochondrial intermembrane space and is primarily responsible for ATP production in hematopoietic cells. AK2 catalyzes the same ADP-to-ATP conversion as AK1 but in the mitochondrial compartment, essential for maintaining cellular energy supply. Mutations in AK2 are linked to reticular dysgenesis, a severe immunodeficiency caused by disrupted leukocyte differentiation. AK2 has critical functions in energy homeostasis during apoptosis, as ATP signaling is necessary for programmed cell death. Its role extends to regulating mitochondrial biogenesis and influencing mitochondrial DNA replication. The expression of AK2 is also vital in early embryonic development and immune system maintenance.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Adenylate Kinase 2 (AK2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 22.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Leu64-Ser232 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

AK2


dry ice

No


availability

Shipped within 5-7 working days.


alias

ADK2


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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