Rat Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) ELISA Kit
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935106861
info@markelab.com
Precio
767€ (96 tests)
Elisa kits for ACSL4
proveedor
Abbexareference
abx500883Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACSL4 is an acyl-CoA synthetase with a strong preference for polyunsaturated fatty acids, such as arachidonic and docosahexaenoic acids, converting them into acyl-CoA derivatives for metabolic use. It is highly expressed in the brain, testis, and adrenal glands, where it supports processes requiring specialized lipid metabolism, including the biosynthesis of eicosanoids and membrane lipids. ACSL4 is critical in ferroptosis, a type of programmed cell death triggered by lipid peroxidation, through its role in incorporating polyunsaturated fatty acids into phospholipids. Dysregulation of ACSL4 has been linked to cancer, neurodegenerative diseases, and inflammatory disorders, as it influences processes such as oxidative stress and cellular survival. Its specific role in handling polyunsaturated fatty acids highlights its importance in maintaining cellular lipid balance and preventing oxidative damage under stress conditions.
Características del producto
category
ELISA Kits
immunogen target
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4)
reactivity
Rat
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.14 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
ACS4,FACL4,LACS4 MRX63,MRX68
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACSL4
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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