Ras-Related Protein Rab-8A (RAB8A) Antibody
442€ (200 µl)
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935106861
info@markelab.com
name
Ras-Related Protein Rab-8A (RAB8A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx433208
tested applications
P-ELISA, WB
Description
RAB8A Antibody is a Goat Polyclonal antibody against RAB8A.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Related Protein Rab-8A (RAB8A) Immunogen: abx615417 - C-Terminus: C-NQGVKITPDQQKR |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 4218 |
| NCBI Accession | NP_005361.2 |
| Alias | Oncogene c-mel,MEL, RAB8,Ras-related protein Rab-8A |
| Background | Antibody anti-RAB8A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
RAB8A, member RAS oncogene family (RAB8A) is a small GTPase involved in regulating intracellular vesicular trafficking, specifically in the transport of vesicles from the Golgi apparatus to the plasma membrane RAB8A is essential for the trafficking of membrane proteins, such as receptors and transporters, and is crucial for the maintenance of cell polarity and membrane dynamics It plays a role in regulating processes like cytokinesis, ciliogenesis, and the establishment of cellular structures by controlling vesicle movement to different regions of the plasma membrane Additionally, RAB8A has been shown to influence neural development and synaptic vesicle trafficking in neurons Dysregulation of RAB8A is associated with several diseases, including neurodegenerative conditions, where its disruption can impair vesicular trafficking and lead to cellular dysfunction RAB8A's involvement in cell signaling, cell cycle regulation, and membrane trafficking also positions it as an important factor in cancer biology and cellular migration
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