Ras-Related Protein Rab-6B (RAB6B) Antibody
383.5€ (100 µl)
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Name
Ras-Related Protein Rab-6B (RAB6B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx224411
Tested Applications
ELISA, WB, IHC, IF/ICC, FCM
Description
Rab6b Antibody is a Mouse Monoclonal against Rab6b.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Related Protein Rab-6B (RAB6B) Immunogen: Purified recombinant fragment of human Rab6b (AA: 95-208) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Observed MW | 23.5 kDa |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NRW1 |
| Gene ID | 51560 |
| OMIM | 615852 |
| Alias | Ras-related protein Rab-6B |
| Background | Antibody anti-RAB6B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB6B, member RAS oncogene family (RAB6B) is a small GTPase involved in regulating intracellular vesicle trafficking, particularly in the post-Golgi network RAB6B is essential for maintaining the proper organization of the Golgi apparatus and controlling vesicle transport between the Golgi and other cellular compartments It is involved in processes like protein sorting, secretion, and recycling, playing a crucial role in the movement of proteins, lipids, and other macromolecules within the cell Additionally, RAB6B is implicated in the regulation of mitosis, where it influences the dynamics of microtubules and membrane fusion during cell division Disruptions in RAB6B function have been associated with several types of cancer, where altered vesicular trafficking contributes to tumor progression, metastasis, and chemotherapy resistance Furthermore, RAB6B also participates in regulating immune responses by controlling the trafficking of immune receptors and cytokines
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