Ras-Related Protein Rab-2A (RAB2A) Antibody

169€ (20 µg)
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935106861
info@markelab.com
name
Ras-Related Protein Rab-2A (RAB2A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx109364
tested applications
ELISA
Description
Ras-Related Protein Rab-2A Antibody is a Rabbit Polyclonal antibody against Ras-Related Protein Rab-2A.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Ras-Related Protein Rab-2A (RAB2A) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P61019 |
Gene ID | 5862 |
NCBI Accession | NP_001229573.1, NM_001242644.1 |
OMIM | 179509 |
Alias | LHX,RAB2,Ras-related protein Rab-2A |
Background | Antibody anti-RAB2A |
Status | RUO |
Descripción
RAB2A, member RAS oncogene family (RAB2A) is a small GTPase that is part of the RAS superfamily of proteins, which regulate intracellular vesicular trafficking and membrane dynamics RAB2A specifically plays a critical role in the transport of vesicles between the endoplasmic reticulum (ER) and the Golgi apparatus, an essential step in the secretory pathway that is crucial for protein sorting, glycosylation, and secretion Additionally, RAB2A is involved in regulating cell cycle progression, vesicular fusion, and cellular responses to stress Dysregulation of RAB2A can lead to various diseases, including cancer, where abnormal vesicular trafficking and cell proliferation are associated with tumor growth and metastasis Furthermore, alterations in RAB2A’s function are also implicated in neurodegenerative diseases, as defects in intracellular protein transport can disrupt cellular homeostasis and contribute to disease pathogenesis
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