Ras-related protein Rab-25 (RAB25) Antibody

Background

RAB25, member RAS oncogene family (RAB25) is a small GTPase that plays a significant role in regulating vesicular trafficking, particularly in the recycling of proteins and lipids within cellular compartments RAB25 is involved in various cellular processes, including the sorting and transport of membrane proteins between endosomes and the plasma membrane, ensuring proper cellular signaling and homeostasis It has been implicated in controlling the movement of integrins, which are crucial for maintaining cell adhesion and migration, especially in epithelial cells RAB25’s role in regulating membrane dynamics also links it to cancer biology, where its dysfunction may contribute to abnormal cell migration, invasion, and metastasis Furthermore, RAB25 has been shown to participate in processes like ciliogenesis, where it regulates the trafficking of proteins to the cilia, impacting cellular signaling pathways related to growth and differentiation RAB25’s involvement in both cancer progression and normal cellular function makes it a potential target for therapeutic intervention, particularly in cancers where altered vesicular trafficking plays a role in tumor progression