Ras-Related Protein Rab-1B (Rab1b) Antibody
383.5€ (100 µl)
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Name
Ras-Related Protein Rab-1B (Rab1b) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx224259
Tested Applications
ELISA, IHC, FCM
Description
Rab1b Antibody is a Mouse Monoclonal against Rab1b.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Related Protein Rab-1B (Rab1b) Immunogen: Purified recombinant fragment of human Rab1b (AA: 60-201) expressed in E. coli. |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG2b |
| Observed MW | 22.2 kDa |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H0U4 |
| Gene ID | 81876 |
| OMIM | 612565 |
| Alias | Ras-related protein Rab-1B |
| Background | Antibody anti-RAB1B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB1B, member RAS oncogene family (RAB1B) is a GTPase closely related to RAB1A and shares many functional similarities in regulating intracellular transport and vesicular trafficking RAB1B is involved in the trafficking of proteins from the ER to the Golgi, as well as the maintenance of membrane integrity and the regulation of cell growth RAB1B helps coordinate the transport of vesicles carrying cargo such as lipids and enzymes, playing a vital role in processes like protein secretion and receptor recycling Like RAB1A, RAB1B is also involved in regulating the organization of the Golgi apparatus and facilitating communication between the ER and Golgi in secretory cells Dysregulation of RAB1B has been associated with cancer, where abnormal vesicular trafficking can promote tumor growth and metastasis Additionally, RAB1B has been implicated in certain viral infections, where it aids in the cellular entry and replication of viruses, further emphasizing its relevance in both cellular function and disease
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