Ras-Related C3 Botulinum Toxin Substrate 2 (RAC2) Antibody
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Description
Ras-Related C3 Botulinum Toxin Substrate 2 (RAC2) Antibody is a Rabbit polyclonal antibody for the detection of Human Ras-Related C3 Botulinum Toxin Substrate 2 (RAC2).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related C3 Botulinum Toxin Substrate 2 (RAC2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P15153 |
| Gene ID | 5880 |
| NCBI Accession | NP_002863.1 |
| Background | Antibody anti-RAC2 |
| Status | RUO |
Descripción
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RAC2 antibody
This gene encodes a member of the Ras superfamily of small guanosine triphosphate (GTP)-metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in this gene are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for this gene on chromosome 6.
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Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species(ROS) by NADPH oxidase.
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