Rabbit Tissue Factor Pathway Inhibitor (TFPI) CLIA Kit
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Pida mas información
935106861
info@markelab.com
Precio
845€ (96 tests)
CLIA Kits TFPI
proveedor
Abbexareference
abx491439Tested Applications
CLIAreactivity
Rabbitstatus
RUOclonality
Descripción
Rabbit Tissue Factor Pathway Inhibitor (TFPI) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Plasma.
Background
Tissue Factor Pathway Inhibitor (TFPI) is a crucial regulator of the extrinsic coagulation cascade, primarily inhibiting the tissue factor (TF)-factor VIIa complex and factor Xa to maintain hemostasis and prevent excessive thrombosis. It is a Kunitz-type serine protease inhibitor, produced mainly by endothelial cells, and circulates bound to lipoproteins or as a free plasma protein. TFPI acts as a feedback inhibitor that ensures balanced thrombin generation, thereby reducing the risk of pathological clot formation. Dysregulation or deficiency in TFPI has been linked to thrombotic disorders and cardiovascular diseases. Beyond its anticoagulant role, TFPI exhibits anti-inflammatory properties, reducing vascular inflammation and protecting against atherosclerosis. It is also involved in angiogenesis and endothelial cell function, making it significant in vascular biology.
Características del producto
category
CLIA Kits
immunogen target
Tissue Factor Pathway Inhibitor (TFPI)
reactivity
Rabbit
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.061 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Chemiluminescent
sample type
Plasma.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
EPI, LACI, TFI, TFPI1,Extrinsic pathway inhibitor,EPI
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
TFPI
dry ice
No
note
The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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