Rabbit Matrix Metalloproteinase 9 (MMP9) Protein

Este producto es parte de MMP9-Matrix Metalloproteinase 9
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234€ (2 µg)

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935106861
info@markelab.com
name
Rabbit Matrix Metalloproteinase 9 (MMP9) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx073928
tested applications
SDS-PAGE

Description

Rabbit Matrix Metalloproteinase-9 is a recombinant enzyme.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryProteins and Peptides
Immunogen TargetMatrix Metalloproteinase 9 (MMP9)
HostInsect
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
OriginRabbit
ExpressionRecombinant
Purity> 85% (SDS-PAGE)
Size 12 µg
Size 210 µg
Size 3100 µg
FormLiquid
Tested ApplicationsSDS-PAGE
AvailabilityShipped within 5-10 working days.
StorageStore at 4 °C if the entire vial will be used within 2-4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP41246
AliasGELB,CLG4B,MMP-9,MANDP2,92 kDa type IV collagenase, Gelatinase B
BackgroundProtein MMP9
StatusRUO
NoteThis product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Matrix metalloproteinase 9 (MMP9), also known as gelatinase B, is an enzyme belonging to the matrix metalloproteinase family. MMP-9 is a zinc-dependent endopeptidase. It is synthesized as a proenzyme, and requires activation by other proteases to become active. The active form of MMP-9 can degrade various components of the extracellular matrix, including collagen type IV, which is a major component of the basement membrane. MMP-9 is implicated in several physiological and pathological processes, including tissue remodeling, angiogenesis, wound healing, inflammation, and cancer metastasis. It is involved in the breakdown of the extracellular matrix, which is essential for processes like tissue repair and remodeling. However, dysregulation of MMP-9 activity can contribute to pathological conditions such as excessive tissue degradation, tumor invasion, and metastasis.MMP-9 activity is tightly regulated at multiple levels, including transcriptional regulation, post-translational modification, and inhibition by tissue inhibitors of metalloproteinases (TIMPs)

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