Rabbit Matrix Metalloproteinase 9 (MMP9) CLIA Kit

Este producto es parte de MMP9-Matrix Metalloproteinase 9
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845€ (96 tests)

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935106861
info@markelab.com
name
Rabbit Matrix Metalloproteinase 9 (MMP9) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx491660
tested applications
CLIA

Description

Rabbit Matrix Metalloproteinase 9 (MMP9) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryCLIA Kits
Immunogen TargetMatrix Metalloproteinase 9 (MMP9)
ReactivityRabbit
Detection MethodChemiluminescent
Assay DataQuantitative
Assay TypeSandwich
Test Range1.56 ng/ml - 100 ng/ml
Sensitivity< 0.57 ng/ml
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
Size 196 tests
Size 25 × 96 tests
Size 310 × 96 tests
FormLyophilized
Tested ApplicationsCLIA
Sample TypeSerum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
AvailabilityShipped within 5-20 working days.
Storage Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry IceNo
UniProt IDP41246
Gene ID100008993
AliasGELB,CLG4B,MMP-9,MANDP2,92 kDa type IV collagenase, Gelatinase B
BackgroundCLIA Kits MMP9
StatusRUO
NoteThe validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Matrix metalloproteinase 9 (MMP9), also known as gelatinase B, is an enzyme belonging to the matrix metalloproteinase family. MMP-9 is a zinc-dependent endopeptidase. It is synthesized as a proenzyme, and requires activation by other proteases to become active. The active form of MMP-9 can degrade various components of the extracellular matrix, including collagen type IV, which is a major component of the basement membrane. MMP-9 is implicated in several physiological and pathological processes, including tissue remodeling, angiogenesis, wound healing, inflammation, and cancer metastasis. It is involved in the breakdown of the extracellular matrix, which is essential for processes like tissue repair and remodeling. However, dysregulation of MMP-9 activity can contribute to pathological conditions such as excessive tissue degradation, tumor invasion, and metastasis.MMP-9 activity is tightly regulated at multiple levels, including transcriptional regulation, post-translational modification, and inhibition by tissue inhibitors of metalloproteinases (TIMPs)

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