Rabbit Matrix Metalloproteinase 3 / Stromelysin-1 (MMP3) Protein
proveedor
Abbexareference
abx654316Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rabbit Matrix Metalloproteinase 3 (MMP3) Protein is a Recombinant Rabbit protein expressed in E. coli.
Background
MMPs are secreted by diverse connective tissue and pro-inflammatory cells. Typically, these enzymes exhibit minimal expression under normal physiological circumstances. MMPs assume a pivotal role in various cellular processes, including cell proliferation, migration, differentiation, angiogenesis, apoptosis, and immunity. They share a common domain structure, consisting of three key components. First is the pro-peptide, which requires removal to activate the enzyme. Next, there is the catalytic domain, featuring a cysteine switch, where a cysteine residue interacts with zinc, and the haemopexin-like C-terminal domain is linked to the catalytic domain via a flexible hinge region. Stromelysin-1, also recognized as matrix metalloproteinase-3 (MMP-3), is an enzyme encoded by the MMP3 gene in humans. Aliases are: CHDS6, MMP-3, SL-1, STMY, STMY1, and STR1.This enzyme plays a significant role in the degradation of fibronectin, laminin, as well as collagens III, IV, IX, and X, along with cartilage proteoglycans. MMP-3 is involved in various biological processes such as wound repair, the progression of atherosclerosis, and the initiation of tumors.
Características del producto
category
Proteins and Peptides
origin
Rabbit
host
E. coli
immunogen target
Matrix Metalloproteinase 3 / Stromelysin-1 (MMP3)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
1 mg
size 2
5 mg
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
MMP3
dry ice
No
availability
Shipped within 1-2 months.
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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