Rabbit Interleukin 17A (IL17A) Protein

Este producto es parte de IL17A - Interleukin 17A
Rabbit Interleukin 17A (IL17A) Protein

Pida mas información

935106861

info@markelab.com

Precio

494€ (50 µg)

Protein IL17A

proveedor

Abbexa

reference

abx067460

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rabbit Interleukin 17A (IL17A) is a recombinant Rabbit protein produced in a Prokaryotic expression system (E. coli).


Background

IL17A is a pro-inflammatory cytokine produced primarily by T-helper 17 (Th17) cells and other immune cells in response to infection and tissue damage IL17A plays a central role in innate and adaptive immunity by stimulating the production of chemokines, cytokines, and antimicrobial peptides that recruit neutrophils and enhance host defense against bacterial and fungal infections Dysregulated IL17A production is associated with autoimmune diseases such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease, where it contributes to chronic inflammation and tissue damage IL17A also plays a role in cancer, where it can promote tumor growth and metastasis by inducing angiogenesis, immune suppression, and chronic inflammation IL17A-targeted therapies, including monoclonal antibodies such as secukinumab, have been developed to treat autoimmune and inflammatory conditions by neutralizing IL17A activity and reducing inflammation

Características del producto

category

Proteins and Peptides


origin

Rabbit


host

E. coli


immunogen target

Interleukin 17A (IL17A)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

50 µg


size 2

100 µg


size 3

200 µg


size 4

500 µg


size 5

1 mg


observerd MW

Molecular Weight: Calculated MW: 16.9 kDa Observed MW (SDS-PAGE): 17 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val21-Ala153 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.6, containing 5% trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IL17A


dry ice

No


availability

Shipped within 5-7 working days.


alias

IL17,CTLA8,IL-1,ILA17,CTLA-8,IL-17A


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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