RAB5B, Member RAS Oncogene Family (RAB5B) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
RAB5B, Member RAS Oncogene Family (RAB5B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx237040
tested applications
ELISA, WB
Description
RAB5B Antibody is a Rabbit Polyclonal against RAB5B.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB5B, Member RAS Oncogene Family (RAB5B) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61020 |
| Gene ID | 5869 |
| OMIM | 179514 |
| Alias | Ras-related protein Rab-5B |
| Background | Antibody anti-RAB5B |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
RAB5B, member RAS oncogene family (RAB5B) is a small GTPase from the RAS superfamily that plays a significant role in the regulation of endocytosis and vesicular trafficking RAB5B is involved in the regulation of early endosomes, controlling their maturation and the internalization of membrane proteins from the cell surface It facilitates the fusion of early endosomes and their movement within the cell to enable proper sorting of internalized cargo for recycling or degradation Additionally, RAB5B is implicated in the regulation of cell signaling and receptor trafficking, which affect various cellular processes, including growth, differentiation, and immune responses Alterations in RAB5B have been linked to a variety of diseases, including cancer, where abnormal vesicular trafficking may contribute to tumorigenesis and metastasis Furthermore, RAB5B also plays roles in neuronal function, impacting synaptic vesicle cycling and neurotransmitter release
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