Human Ras-Related Protein Rab-3A (RAB3A) Protein

Este producto es parte de RAB - member RAS oncogene family
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234€ (2 µg)

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935106861
info@markelab.com
name
Human Ras-Related Protein Rab-3A (RAB3A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262903
tested applications
SDS-PAGE

Description

Ras-Related Protein Rab-3A (RAB3A) is a recombinant protein consisting of a single, non-glycosylated polypeptide chain containing 240 amino acids, expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Ras-Related Protein Rab-3A (RAB3A)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: 1-220 AA.
Tag: N-terminal His tag
Origin
Human
Conjugation
Unconjugated
Observed MW
27.1 kDa
Expression
Recombinant
Purity
> 90% (SDS-PAGE) <br> Sterile filtered.
Purification
Purified by proprietary chromatography techniques.
Size 1
2 µg
Size 2
10 µg
Size 3
1 mg
Form
Liquid
Tested Applications
SDS-PAGE
Buffer
20 mM Tris-HCl, pH 8.0, containing 20% Glycerol, 0.1 M NaCl and 1 mM DTT.
Availability
Shipped within 5-10 working days.
Storage
Store at 4°C for up to 4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P20336
Alias
Ras-related protein Rab-3A,RAS-associated protein RAB3A
Background
Protein RAB3A
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Concentration: 0.5 mg/ml

Descripción

RAB3A, member RAS oncogene family (RAB3A) is another small GTPase that is primarily involved in regulating vesicular trafficking, particularly in neurons and endocrine cells RAB3A plays a pivotal role in the regulated release of neurotransmitters and hormones through its involvement in synaptic vesicle recycling and exocytosis It is essential for the proper functioning of synapses, where it helps control the fusion of synaptic vesicles with the plasma membrane, allowing for neurotransmitter release and signal transmission between neurons In addition to its function in neurotransmission, RAB3A is also involved in insulin secretion in pancreatic beta cells Dysregulation of RAB3A is associated with neurological disorders, such as epilepsy and neurodegenerative diseases, as well as metabolic disorders like diabetes, where impaired vesicle trafficking and hormone release contribute to disease progression Understanding RAB3A’s role in cellular transport and neurotransmission is critical for developing therapeutic strategies for neurological and metabolic diseases
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