RAB25, Member RAS Oncogene Family (RAB25) Antibody
312€ (60 µl)
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Name
RAB25, Member RAS Oncogene Family (RAB25) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx126445
Tested Applications
WB
Description
RAB25 Antibody is a Rabbit Polyclonal against RAB25.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: RAB25, Member RAS Oncogene Family (RAB25) Immunogen: Recombinant fusion protein corresponding to human RAB25 |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 23 kDa Observed MW: 23 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P57735 |
| Gene ID | 57111 |
| NCBI Accession | NP_065120.2 |
| Alias | CATX-8,RAB11C,Ras-related protein Rab-25 |
| Background | Antibody anti-RAB25 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB25, member RAS oncogene family (RAB25) is a small GTPase that plays a significant role in regulating vesicular trafficking, particularly in the recycling of proteins and lipids within cellular compartments RAB25 is involved in various cellular processes, including the sorting and transport of membrane proteins between endosomes and the plasma membrane, ensuring proper cellular signaling and homeostasis It has been implicated in controlling the movement of integrins, which are crucial for maintaining cell adhesion and migration, especially in epithelial cells RAB25’s role in regulating membrane dynamics also links it to cancer biology, where its dysfunction may contribute to abnormal cell migration, invasion, and metastasis Furthermore, RAB25 has been shown to participate in processes like ciliogenesis, where it regulates the trafficking of proteins to the cilia, impacting cellular signaling pathways related to growth and differentiation RAB25’s involvement in both cancer progression and normal cellular function makes it a potential target for therapeutic intervention, particularly in cancers where altered vesicular trafficking plays a role in tumor progression
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