RAB23, Member RAS Oncogene Family (RAB23) Antibody
442€ (200 µl)
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935106861
info@markelab.com
name
RAB23, Member RAS Oncogene Family (RAB23) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431545
tested applications
P-ELISA, WB
Description
RAB23 Antibody is a Goat Polyclonal antibody against RAB23.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: RAB23, Member RAS Oncogene Family (RAB23) Immunogen: abx615419 - C-Terminus: C-PNKQRTKKNRNP |
| Host | Goat |
| Reactivity | Mouse |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 51715, 19335, 367242 |
| NCBI Accession | NP_057361.3, NP_899050.1 |
| Alias | HSPC137,Ras-related protein Rab-23 |
| Background | Antibody anti-RAB23 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
RAB23, member RAS oncogene family (RAB23) is a small GTPase that regulates the trafficking of intracellular vesicles and plays a role in the movement of molecules between the endosomal system and other cellular compartments, including the Golgi apparatus and plasma membrane RAB23 has been shown to participate in the process of autophagy, where it helps in the sorting and degradation of cellular materials via the lysosomal pathway, ensuring that damaged or unwanted components are properly processed and removed from the cell This function links RAB23 to cellular stress responses, maintaining cellular integrity and preventing the accumulation of damaged proteins and organelles Additionally, RAB23 is involved in regulating the function of the sonic hedgehog signaling pathway, which is critical for development and the control of cellular proliferation RAB23’s dysfunction is linked to various genetic disorders, including craniofacial malformations, where defects in its trafficking function disrupt proper cellular signaling and tissue development Furthermore, RAB23 is involved in cancer biology, where aberrant vesicular trafficking contributes to uncontrolled cell growth, tumor progression, and metastasis
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