RAB22A-specific Antibody
364€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
RAB22A-specific Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx237005
tested applications
ELISA, WB
Description
RAB22A-specific Antibody is a Rabbit Polyclonal against RAB22A-specific.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB22A-specific |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UL26 |
| Gene ID | 57403 |
| OMIM | 612966 |
| Alias | RAB22,Ras-related protein Rab-22A |
| Background | Antibody anti-RAB22A |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
RAB22A, member RAS oncogene family (RAB22A) is a member of the RAB family of small GTPases that plays a pivotal role in regulating vesicular trafficking, particularly in the recycling of proteins and lipids within cellular compartments RAB22A is involved in the movement of vesicles between endosomes and the plasma membrane, ensuring the proper sorting and trafficking of receptors, proteins, and other key molecules to their intended destinations It also regulates the dynamic processes of endocytosis and exocytosis, which are crucial for maintaining cellular homeostasis, signal transduction, and membrane recycling RAB22A is particularly important for controlling the trafficking of molecules that participate in cell-cell adhesion and the modulation of the extracellular matrix, impacting cell migration, wound healing, and tissue repair In cancer, RAB22A has been implicated in promoting metastasis by influencing cell adhesion and migration, leading to uncontrolled tumor spread Additionally, RAB22A is involved in immune cell trafficking, which affects inflammatory responses and immune system regulation Dysregulation of RAB22A’s activity can contribute to various pathologies, including neurodegenerative diseases, cancer, and immune disorders
Related Products
RAB22A antibody
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
Ver ProductoRAB22A-specific antibody
Ver Producto