RAB22A, Member RAS Oncogene Family (RAB22A) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
RAB22A, Member RAS Oncogene Family (RAB22A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx030618
tested applications
ELISA, WB
Description
The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB22A, Member RAS Oncogene Family (RAB22A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UL26 |
| Alias | RAB22,Ras-related protein Rab-22A |
| Background | Antibody anti-RAB22A |
| Status | RUO |
Descripción
RAB22A, member RAS oncogene family (RAB22A) is a member of the RAB family of small GTPases that plays a pivotal role in regulating vesicular trafficking, particularly in the recycling of proteins and lipids within cellular compartments RAB22A is involved in the movement of vesicles between endosomes and the plasma membrane, ensuring the proper sorting and trafficking of receptors, proteins, and other key molecules to their intended destinations It also regulates the dynamic processes of endocytosis and exocytosis, which are crucial for maintaining cellular homeostasis, signal transduction, and membrane recycling RAB22A is particularly important for controlling the trafficking of molecules that participate in cell-cell adhesion and the modulation of the extracellular matrix, impacting cell migration, wound healing, and tissue repair In cancer, RAB22A has been implicated in promoting metastasis by influencing cell adhesion and migration, leading to uncontrolled tumor spread Additionally, RAB22A is involved in immune cell trafficking, which affects inflammatory responses and immune system regulation Dysregulation of RAB22A’s activity can contribute to various pathologies, including neurodegenerative diseases, cancer, and immune disorders
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