RAB17, Member RAS Oncogene Family (Rab17) Antibody
416€ (200 µl)
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935106861
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name
RAB17, Member RAS Oncogene Family (Rab17) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431544
tested applications
P-ELISA, WB
Description
Rab17 Antibody is a Goat Polyclonal antibody against Rab17.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB17, Member RAS Oncogene Family (Rab17) |
| Host | Goat |
| Reactivity | Mouse |
| Recommended Dilution | P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 19329, 503269 |
| NCBI Accession | NP_033024.1 |
| Alias | Ras-related protein Rab-17 |
| Background | Antibody anti-RAB17 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
RAB17, member RAS oncogene family (RAB17) is involved in regulating vesicle trafficking between various cellular compartments, including the Golgi apparatus, endosomes, and the plasma membrane RAB17 is important for maintaining the recycling of membrane proteins and internalized receptors, ensuring proper cellular signaling and the recycling of molecules involved in cell surface receptor activity It has been implicated in controlling membrane dynamics, particularly in processes related to vesicle formation, membrane fusion, and cell polarity RAB17 also plays a role in regulating actin dynamics, which is essential for cell motility and tissue remodeling, particularly in epithelial cells where proper adhesion and junction formation are critical Its dysfunction is linked to a variety of diseases, including cancer, where dysregulated vesicular trafficking may promote metastasis by enhancing cell migration and altering receptor activity Additionally, RAB17 is involved in the immune response by regulating the trafficking of immune receptors, impacting inflammation and cell communication during immune activation
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