Rab GDP Dissociation Inhibitor Alpha (GDI1) Antibody

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Description
Rab GDP Dissociation Inhibitor Alpha (GDI1) Antibody is a Rabbit polyclonal antibody for the detection of Human Rab GDP Dissociation Inhibitor Alpha (GDI1).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Rab GDP Dissociation Inhibitor Alpha (GDI1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P31150 |
Gene ID | 2664 |
NCBI Accession | NP_001484.1 |
Background | Antibody anti-GDI1 |
Status | RUO |
Descripción
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GDI1 antibody
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
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GDI1 antibody
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation. Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
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