Rab Effector MyRIP (MYRIP) Antibody (FITC)
169€ (20 µg)
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935106861
info@markelab.com
name
Rab Effector MyRIP (MYRIP) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx317556
Description
MYRIP Antibody (FITC) is a Rabbit Polyclonal against MYRIP conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Rab Effector MyRIP (MYRIP) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFW9 |
| Gene ID | 25924 |
| NCBI Accession | NP_001271352.1, NM_001284423.1 |
| OMIM | 611790 |
| Alias | SLAC2C,SLAC2-C,Rab effector MyRIP,Exophilin-8,Myosin-VIIa- and Rab-interacting protein,synaptotagmin-like protein homologue lacking C2 domains-c |
| Background | Antibody anti-MYRIP |
| Status | RUO |
Descripción
Myosin VIIA and Rab interacting protein (MYRIP) is a protein that interacts with both myosin VIIA (MYO7A) and Rab proteins, which are involved in cellular transport and vesicular trafficking MYRIP acts as an adaptor protein, linking the motor protein MYO7A to Rab GTPases, which are involved in the regulation of vesicle movement within cells MYRIP is especially important in sensory cells, such as the photoreceptor cells in the retina and hair cells in the inner ear, where it aids in the transport of cargo along actin filaments and ensures proper cellular function MYRIP’s role in facilitating the transport of proteins and organelles to their correct locations within cells is critical for maintaining the integrity of sensory cells, and disruptions in MYRIP function are associated with retinitis pigmentosa and hearing loss MYRIP’s involvement in both auditory and visual sensory function highlights its importance for sensory health
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