Rab Effector MyRIP (MYRIP) Antibody
442€ (200 µl)
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935106861
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name
Rab Effector MyRIP (MYRIP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx430567
tested applications
P-ELISA, WB, IHC
Description
MYRIP Antibody is a Goat Polyclonal antibody against MYRIP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Rab Effector MyRIP (MYRIP) Immunogen: abx269372 - C-Terminus: C-KDLMEPALESAVMY |
| Host | Goat |
| Reactivity | Human |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/64000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 25924 |
| NCBI Accession | NP_056275.2 |
| Alias | SLAC2C,SLAC2-C,Rab effector MyRIP,Exophilin-8,Myosin-VIIa- and Rab-interacting protein,synaptotagmin-like protein homologue lacking C2 domains-c |
| Background | Antibody anti-MYRIP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Myosin VIIA and Rab interacting protein (MYRIP) is a protein that interacts with both myosin VIIA (MYO7A) and Rab proteins, which are involved in cellular transport and vesicular trafficking MYRIP acts as an adaptor protein, linking the motor protein MYO7A to Rab GTPases, which are involved in the regulation of vesicle movement within cells MYRIP is especially important in sensory cells, such as the photoreceptor cells in the retina and hair cells in the inner ear, where it aids in the transport of cargo along actin filaments and ensures proper cellular function MYRIP’s role in facilitating the transport of proteins and organelles to their correct locations within cells is critical for maintaining the integrity of sensory cells, and disruptions in MYRIP function are associated with retinitis pigmentosa and hearing loss MYRIP’s involvement in both auditory and visual sensory function highlights its importance for sensory health
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