Pyruvate Dehydrogenase Kinase 1 (PDK1) Peptide
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Description
Pyruvate Dehydrogenase Kinase 1 (PDK1) Peptide is a synthetic peptide. This peptide is used in the production of
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Pyruvate Dehydrogenase Kinase 1 (PDK1) |
| Host | Synthetic |
| Assay Type | Activity: Not tested. Sequence Fragment: Internal region: C-DFKDKSAEDAK |
| Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | P-ELISA |
| Buffer | Prior to lyophilization: Deionized water. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 5163 |
| NCBI Accession | NP_002601.1 |
| Background | Protein PDK1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in deionized water. |
Descripción
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PDK1 antibody
Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
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Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.
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