Pyrroline-5-Carboxylate Reductase 1, Mitochondrial (PYCR1) Antibody (HRP)
169€ (20 µg)
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935106861
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name
Pyrroline-5-Carboxylate Reductase 1, Mitochondrial (PYCR1) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx108689
tested applications
ELISA
Description
Pyrroline-5-carboxylate reductase 1, mitochondrial Antibody (HRP) is a Rabbit Polyclonal antibody against Pyrroline-5-carboxylate reductase 1, mitochondrial conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Pyrroline-5-Carboxylate Reductase 1, Mitochondrial (PYCR1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P32322 |
| Gene ID | 5831 |
| NCBI Accession | NP_001269209.1, NM_001282280.1 |
| OMIM | 179035 |
| Background | Antibody anti-PYCR1 |
| Status | RUO |
Descripción
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This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternative splicing results in multiple transcript variants.
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Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress.
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