Putative Activator of 90 kDa Heat Shock Protein ATPase Homolog 2 (AHSA2) Antibody
169€ (20 µg)
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name
Putative Activator of 90 kDa Heat Shock Protein ATPase Homolog 2 (AHSA2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx307785
tested applications
ELISA, WB, IHC
Description
AHSA2 Antibody is a Rabbit Polyclonal against AHSA2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Putative Activator of 90 kDa Heat Shock Protein ATPase Homolog 2 (AHSA2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q719I0 |
| Gene ID | 130872 |
| NCBI Accession | NP_001308229.1, NM_001321300.1 |
| Alias | AHA1, C14orf3, hAha1, p38 |
| Background | Antibody anti-AHSA1 |
| Status | RUO |
Descripción
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHSA1) is a co-chaperone protein that enhances the ATPase activity of Hsp90, a molecular chaperone essential for the proper folding, stability, and function of numerous client proteins, including kinases, receptors, and transcription factors. AHSA1 facilitates the Hsp90 chaperone cycle, ensuring efficient protein maturation and stress response. Overexpression of AHSA1 has been linked to cancer, as it enhances the stability of oncogenic client proteins required for tumor progression and survival. AHSA1 is a promising target for cancer therapies aimed at disrupting Hsp90 function. Beyond cancer, AHSA1 also plays a role in protein quality control and cellular stress responses, contributing to proteostasis under normal and pathological conditions.
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