PR/SET Domain 14 (PRDM14) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
PRDM14 Antibody is a Rabbit Polyclonal against PRDM14.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | PR/SET Domain 14 (PRDM14) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/2000 - 1/10000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9GZV8 |
| Gene ID | 63978 |
| Background | Antibody anti-PRDM14 |
| Status | RUO |
Descripción
Related Products
PR/SET Domain 14 (PRDM14) Antibody
PRDM14 Antibody is a Rabbit Polyclonal antibody against PRDM14. This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer.
Ver Producto
PR/SET Domain 14 (PRDM14) Antibody
PRDM14 Antibody is a Rabbit Polyclonal antibody against PRDM14.
Ver Producto
PR/SET Domain 14 (PRDM14) Antibody
Similar to acetylation and phosphorylation, histone methylation at the N terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET domain containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET domain family, and another 17 make up the PR domain family that is related to the SET domain family. PRDM14 is part of a family of PR domain genes that are involved in tumorigenesis. It may function as a transcription factor.
Ver Producto