Proto-Oncogene Vav (VAV1) Antibody

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Proto-Oncogene Vav (VAV1) Antibody is a Rabbit polyclonal antibody for the detection of Human Proto-Oncogene Vav (VAV1).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Proto-Oncogene Vav (VAV1) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P15498 |
Gene ID | 7409 |
NCBI Accession | NP_001245136.1 |
Alias | VAV1, VAV,VAV1 protein,Proto-oncogene vav |
Background | Antibody anti-VAV1 |
Status | RUO |
Descripción
Related Products

VAV1 antibody
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Ver Producto
Recombinant Human VAV1
Ver Producto
VAV1 (pY174) Antibody
VAV1 (pY174) Antibody is a Rabbit Polyclonal antibody against VAV1 (pY174). This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Ver Producto