Protein Wnt-3a (WNT3A) Antibody
468€ (100 µl)
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935106861
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name
Protein Wnt-3a (WNT3A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx117009
tested applications
ELISA, WB, IHC
Description
WNT3A Antibody is a Rabbit Polyclonal antibody against WNT3A. The Wnt family includes several secreted glycoproteins that play important roles in animal developmentThere are 19 Wnt genes in the human genome that encode functionally distinct Wnt proteinsWnt members bind to the Frizzled family of seven-pass transmembrane proteins and activate several signaling pathwaysThe canonical Wnt/β-catenin pathway also requires a coreceptor from the low-density lipoprotein receptor familyAberrant activation of Wnt signaling pathways is involved in several types of cancersWnt3a protein is palmitoylated and can function as a growth factor for hematopoietic stem cellsAlthough functionally distinct, Wnt3a shows high homology to Wnt3This protein is involved in Signal Transduction.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Protein Wnt-3a (WNT3A) Immunogen: Recombinant protein of human WNT3A. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 2.68 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P56704 |
| Gene ID | 89780 |
| Background | Antibody anti-WNT3A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region.
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