Protein unc-13 homolog B (UNC13B) Antibody (FITC)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Protein unc-13 homolog B (UNC13B) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human UNC13B.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Protein unc-13 homolog B (UNC13B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Size 3 | 200 µl |
| Size 4 | 1 ml |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O14795 |
| Gene ID | 10497 |
| OMIM | 605836 |
| Background | Antibody anti-UNC13B |
| Status | RUO |
Descripción
Related Products
Protein Unc-13 Homolog B (UNC13B) Antibody
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq].
Ver Producto
Protein Unc-13 Homolog B (UNC13B) Antibody
UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
Ver Producto
Protein unc-13 homolog B (UNC13B) Antibody
Protein unc-13 homolog B (UNC13B) Antibody is a Rabbit Polyclonal antibody for the detection of Human UNC13B.
Ver Producto