Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody
351€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx375959
Tested Applications
ELISA, WB
Description
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody is a Rabbit Polyclonal antibody against Protein Tyrosine Phosphatase Receptor Type G (PTPRG).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Immunogen: Synthesized peptide derived from a partial region of the human protein. |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | ELISA: 1/5000 - 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P23470 |
| Gene ID | 5793 |
| OMIM | 176886 |
| Alias | PTPG,HPTPG,RPTPG,R-PTP-GAMMA,Protein-tyrosine phosphatase gamma,Receptor-type tyrosine-protein phosphatase gamma |
| Background | Antibody anti-PTPRG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
PTPRG is a receptor-type protein tyrosine phosphatase that plays a key role in tumor suppression, immune regulation, and nervous system development. Structurally, PTPRG contains extracellular carbonic anhydrase-like and fibronectin type III domains, a transmembrane region, and two cytoplasmic phosphatase domains. PTPRG is expressed in various tissues, particularly in the brain and immune system. It regulates cellular signaling by dephosphorylating receptor tyrosine kinases (RTKs), thereby influencing cell proliferation, adhesion, and migration. PTPRG has been identified as a tumor suppressor gene in cancers such as lung, breast, and colorectal cancers. In addition, its involvement in synaptic plasticity and neuronal repair highlights its significance in neurobiology. Loss of PTPRG expression through methylation or mutations contributes to tumorigenesis and neurological disorders.
Productos relacionados
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be sign…
Ver producto
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody
Protein Tyrosine Phosphatase Receptor Type G Antibody is a Rabbit Polyclonal against Protein Tyrosine Phosphatase Recept…
Ver producto
Human Protein Tyrosine Phosphatase Receptor Type G (PTPRG) ELISA Kit
Human Protein Tyrosine Phosphatase Receptor Type G (PTPRG) ELISA Kit is an ELISA Kit for the in vitro quantitative measu…
Ver producto