Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Protein Tyrosine Phosphatase Receptor Type G (PTPRG) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | PTPG,HPTPG,RPTPG,R-PTP-GAMMA,Protein-tyrosine phosphatase gamma,Receptor-type tyrosine-protein phosphatase gamma |
| Background | Antibody anti-PTPRG |
| Status | RUO |
Descripción
PTPRG is a receptor-type protein tyrosine phosphatase that plays a key role in tumor suppression, immune regulation, and nervous system development. Structurally, PTPRG contains extracellular carbonic anhydrase-like and fibronectin type III domains, a transmembrane region, and two cytoplasmic phosphatase domains. PTPRG is expressed in various tissues, particularly in the brain and immune system. It regulates cellular signaling by dephosphorylating receptor tyrosine kinases (RTKs), thereby influencing cell proliferation, adhesion, and migration. PTPRG has been identified as a tumor suppressor gene in cancers such as lung, breast, and colorectal cancers. In addition, its involvement in synaptic plasticity and neuronal repair highlights its significance in neurobiology. Loss of PTPRG expression through methylation or mutations contributes to tumorigenesis and neurological disorders.
Related Products
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
Ver Producto
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Antibody
Protein Tyrosine Phosphatase Receptor Type G Antibody is a Rabbit Polyclonal against Protein Tyrosine Phosphatase Receptor Type G.
Ver Producto
Human Protein Tyrosine Phosphatase Receptor Type G (PTPRG) ELISA Kit
Human Protein Tyrosine Phosphatase Receptor Type G (PTPRG) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Protein Tyrosine Phosphatase Receptor Type G (PTPRG) concentrations in tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Protein Tyrosine Phosphatase Receptor Type G (PTPRG)
Ver Producto