Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) Antibody
169€ (20 µl)
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935106861
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name
Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx321342
tested applications
ELISA, IHC
Description
PPFIA1 Antibody is a Rabbit Polyclonal against PPFIA1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Protein Tyrosine Phosphatase F Interacting Protein 1 (PPFIA1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13136 |
| Gene ID | 8500 |
| NCBI Accession | NP_003617.1, NM_003626.3, NP_803172.1, NM_177423.2 |
| OMIM | 611054 |
| Background | Antibody anti-PPFIA1 |
| Status | RUO |
Descripción
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The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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