Protein Lin-7 Homolog A (LIN7A) Antibody

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Description
Protein Lin-7 Homolog A (LIN7A) Antibody is a Rabbit Polyclonal antibody against Protein Lin-7 Homolog A (LIN7A).
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Protein Lin-7 Homolog A (LIN7A) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Purification | Purified by affinity chromatography using epitope-specific immunogen. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O14910 |
Gene ID | 8825 |
Background | Antibody anti-LIN7A |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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LIN7A antibody
Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7(LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B(subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter(SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
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Protein Lin-7 Homolog A (LIN7A) Antibody
LIN7A plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
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