Protein Kinase C Gamma (PRKCG) Antibody (ATTO488)
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Description
PKC gamma Antibody (ATTO488) is a Rabbit Polyclonal Antibody against PRKCG.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Protein Kinase C Gamma (PRKCG) Immunogen: Synthetic peptide from the mid-protein of Human PRKCG (aa. 150-250). |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Detection Method | Laser Line: 488 Excitation/Emission: 500/520 |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/1000, IHC: 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | ATTO488 |
| Purification | Peptide Affinity Purified |
| Size 1 | 100 µg |
| Tested Applications | WB, IHC |
| Buffer | PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at 4°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P05129 |
| Gene ID | 5582 |
| NCBI Accession | NP_001303258.1 |
| Background | Antibody anti-PRKCG |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.
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Protein kinase C(PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC gamma is a neuron-specific member of the classical PKCs and is activated and translocated to subcellular regions as a result of various stimuli, including diacylglycerol synthesis, increased intracellular Ca(2+) and phorbol esters. Defects in this protein have been associated with spinocerebellar ataxia type 14(SCA14), an autosomal dominant neurodegenerative disease.
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