Protein C Inhibitor (SERPINA5) Antibody

292.5€ (80 µl)
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name
Protein C Inhibitor (SERPINA5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028591
tested applications
ELISA, WB
Description
Protein C Inhibitor (SERPINA5) inhibits activated protein C as well as plasminogen activators.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Protein C Inhibitor (SERPINA5) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Size 1 | 80 µl |
Size 2 | 400 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P05154 |
Alias | PCI,PAI3,PAI-3; PCI-B,PROCI,PLANH3,Plasma serine protease inhibitor,Plasminogen activator inhibitor 3,Protein C inhibitor,Serpin A5 Acrosomal serine protease inhibitor |
Background | Antibody anti-SERPINA5 |
Status | RUO |
Descripción
SERPINA5, also known as protein C inhibitor (PCI), is a member of the serpin (serine protease inhibitor) superfamily. This gene encodes a protein that plays a crucial role in the regulation of proteolytic processes, particularly those involved in the coagulation and fibrinolysis pathways. Located on chromosome 14q32.13, the SERPINA5 gene is part of the SERPIN family, which is characterized by its ability to inhibit serine proteases through a conserved reactive center loop (RCL) mechanism. SERPINA5 is primarily expressed in the liver, but it is also found in a wide range of tissues, including the kidney, testis, and seminal plasma. The protein encoded by SERPINA5 is involved in the inhibition of several key proteases, including activated protein C, which plays a critical role in the regulation of blood coagulation
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