Protein AMBP (AMBP) Protein

234€ (2 µg)
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name
Protein AMBP (AMBP) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx262923
tested applications
SDS-PAGE
Description
AMBP is a recombinant protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | AMBP |
Conjugation | Unconjugated |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 2 µg |
Size 2 | 10 µg |
Size 3 | 1 mg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Dry Ice | No |
UniProt ID | P02760 |
Alias | A1M,HCP,ITI,UTI,EDC1,HI30,ITIL,IATIL,ITILC,AMBP |
Background | Protein AMBP |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Alpha-1-Microglobulin-Bikunin Precursor (AMBP) encodes a precursor protein that generates two distinct products: alpha-1-microglobulin (A1M) and bikunin. Alpha-1-microglobulin is a small glycoprotein with potent antioxidant and anti-inflammatory properties, primarily involved in scavenging free heme and protecting tissues from oxidative stress and protein damage. It also binds and removes oxidized molecules, maintaining cellular homeostasis. Bikunin, on the other hand, is a Kunitz-type protease inhibitor that regulates serine proteases, playing a key role in controlling inflammation and extracellular matrix stabilization. As part of the inter-alpha-trypsin inhibitor family, bikunin contributes to tissue repair and proteolytic balance. Both proteins are primarily produced in the liver and circulate in the blood, fulfilling complementary functions in tissue protection and repair. Dysregulation of AMBP expression has been implicated in liver diseases, chronic inflammation, and cancer, where disruptions in antioxidant defense, protease regulation, and extracellular matrix stability contribute to disease progression, highlighting its importance in maintaining physiological homeostasis.
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