Proteasome Subunit Beta Type-2 (PSMB2) Antibody

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Description
Proteasome Subunit Beta Type-2 (PSMB2) Antibody is a Rabbit polyclonal antibody for the detection of Human Proteasome Subunit Beta Type-2 (PSMB2).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | Proteasome Subunit Beta Type-2 (PSMB2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P49721 |
Gene ID | 5690 |
NCBI Accession | NP_002785.1 |
Background | Antibody anti-PSMB2 |
Status | RUO |
Descripción
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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