Prominin-1 (PROM1) Antibody (FITC)
429€ (200 µl)
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Name
Prominin-1 (PROM1) Antibody (FITC)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx274395
Tested Applications
WB, IHC, IF/ICC
Description
Prominin-1 (PROM1) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Prominin-1 (PROM1).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Prominin-1 (PROM1) |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 4°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43490 |
| Gene ID | 8842 |
| OMIM | 604365 |
| Alias | RP41,AC133,CD133,MCDR2,STGD4,CORD12,PROML1,MSTP061,Prominin-like protein 1 |
| Background | Antibody anti-PROM1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Prominin-1 (PROM1), also known as CD133, is a transmembrane glycoprotein that plays a significant role in stem cell biology and cellular development. Widely recognized as a marker for stem and progenitor cells in various tissues, PROM1 is expressed on the apical surface of epithelial and hematopoietic stem cells. It participates in cellular differentiation and is crucial for maintaining the stem cell niche, with implications in tissue regeneration and repair. PROM1 has become a focus of research due to its role in cell signaling and its involvement in numerous developmental pathways, including those of the nervous system, retina, and digestive tract. Additionally, aberrant PROM1 expression is associated with cancer, specifically in cancer stem cells, and its presence is often used as a marker to identify cells with tumorigenic potential. PROM1’s relevance to cellular organization and tissue homeostasis, along with its association with pathological conditions, makes it an important molecule in cell biology and oncology.
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