Programmed Cell Death 1 Ligand 1 (CD274) Antibody Pair

Este producto es parte de CD274 molecule
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1261€ (5 × 96 tests)

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935106861
info@markelab.com
name
Programmed Cell Death 1 Ligand 1 (CD274) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370587
tested applications
ELISA

Description

Programmed Cell Death Protein 1 Ligand 1 (PDCD1LG1) Antibody Pair for use in Sandwich ELISA assay development. 

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Antibody Pairs
Immunogen Target
Programmed Cell Death 1 Ligand 1 (CD274)
Reactivity
Human
Assay Data
Capture: Rabbit  Polyclonal
Detection:  Rabbit  Polyclonal (Biotin)
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Dilute the Capture Antibody 125-fold with Coating Buffer.  Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent.  Optimal dilutions/concentrations should be determined by the end user.
Size 1
5 × 96 tests
Size 2
10 × 96 tests
Form
Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody)
Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user. The recommended reconstitution volume is 1.0 ml for a standard curve range of 0.156 ng/ml - 10 ng/ml.
Tested Applications
ELISA
Buffer
The Capture and Detection Antibody both contain 0.1% sodium azide.
Availability
Shipped within 5-20 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
B7-H,B7H1,PDL,PD-L1,hPD-L1,PDCD1L1,PDCD1LG1,B7 homolog 1,PDCD1 ligand 1,Programmed death ligand 1,Programmed cell death 1 ligand 1
Background
Antibody Pair for CD274
Status
RUO
Note
This antibody pair contains ( 5 x 96 det):    Detection:  50 µg  Capture:  200 µg  Standard:  2 µg
This product is for research use only.

Descripción

CD274 molecule, also known as Programmed Death-Ligand 1 (PD-L1), is a critical component in the immune checkpoint pathway. Encoded by the CD274 gene located on chromosome 9p24.1, PD-L1 is primarily expressed on the surface of various cell types, including immune cells (such as T cells, B cells, dendritic cells, and macrophages) and non-immune cells (including epithelial and endothelial cells). Its expression can be upregulated in response to inflammatory signals, particularly interferon-gamma (IFN-γ). PD-L1 plays a vital role in maintaining immune homeostasis and preventing autoimmunity by regulating the activity of T cells. PD-L1 gained significant attention in cancer immunotherapy due to its role in tumor immune evasion. Many tumors exploit the PD-1/PD-L1 pathway to suppress anti-tumor immune responses, allowing cancer cells to escape immune surveillance

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