Pregnancy Zone Protein (PZP) Antibody Pair

1612€ (5 × 96 tests)
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935106861
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name
Pregnancy Zone Protein (PZP) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370759
tested applications
ELISA
Description
Pregnancy Zone Protein (PZP) Antibody Pair for use in Sandwich ELISA assay development.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Antibody Pairs |
Immunogen Target | Pregnancy Zone Protein (PZP) |
Reactivity | Rat |
Assay Data | Detection Antibody Biotinilated |
Assay Type | Sandwich |
Recommended Dilution | Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 5 × 96 tests |
Size 2 | 10 × 96 tests |
Form | Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody) Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user. |
Tested Applications | ELISA |
Buffer | The Capture and Detection Antibody both contain 0.1% sodium azide. |
Availability | Please enquire. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | CPAMD6,pregnancy zone protein,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6 |
Background | Antibody Pair for PZP |
Status | RUO |
Note | This antibody pair contains ( 5 x 96 det): Detection: 50 µg Capture: 200 µg Standard: 2 µg This product is for research use only. |
Descripción
PZP alpha-2-macroglobulin like (PZP) is a protein that shares structural similarities with alpha-2-macroglobulin, a major inhibitor of proteases in the blood, and functions in regulating immune responses and tissue repair PZP is involved in inhibiting a wide range of proteases, including those involved in inflammation and coagulation, thereby preventing tissue damage caused by excessive protease activity It is expressed in various tissues, including the liver and brain, and has been shown to modulate immune cell activation and inflammatory processes PZP’s role in protease inhibition also extends to its involvement in preventing excessive tissue degradation during injury and infection, contributing to wound healing and tissue remodeling Dysregulation of PZP expression has been linked to inflammatory diseases, including autoimmune conditions, where its altered levels can exacerbate inflammation and tissue damage Furthermore, PZP has been implicated in cancer, where it may influence tumor progression by regulating protease activity within the tumor microenvironment Studies suggest that PZP may also have neuroprotective effects, particularly in diseases like Alzheimer’s, where it modulates protease activity in the brain to reduce neuronal damage
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