Potassium Voltage-Gated Channel Subfamily A Member 5 (KCNA5) Antibody
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Description
KCNA5 Antibody is a Rabbit Polyclonal against KCNA5.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Potassium Voltage-Gated Channel Subfamily A Member 5 (KCNA5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P22460 |
| Gene ID | 3741 |
| Background | Antibody anti-KCNA5 |
| Status | RUO |
Descripción
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Human KCNA5 (Potassium voltage-gated channel subfamily A member 5) ELISA Kit
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KCNA5 antibody
Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane. Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNA1, KCNA2, KCNA4, KCNA5, and possibly other family members as well; channel properties depend on the type of alpha subunits that are part of the channel(PubMed:12130714). Channel properties are modulated by cytoplasmic beta subunits that regulate the subcellular location of the alpha subunits and promote rapid inactivation(PubMed:12130714). Homotetrameric channels display rapid activation and slow inactivation(PubMed:8505626, PubMed:12130714). May play a role in regulating the secretion of insulin in normal pancreatic islets. Isoform 2 exhibits a voltage-dependent recovery from inactivation and an excessive cumulative inactivation(PubMed:11524461).
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Potassium Voltage-Gated Channel Subfamily A Member 5 (KCNA5) Antibody
Rabbit polyclonal antibody against KCNA5 protein. Immunogen region is Internal.
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