Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3) Antibody

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260€ (50 µg)

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935106861
info@markelab.com
name
Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx377937
tested applications
ELISA, WB, IHC

Description

Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3) Antibody is a Rabbit polyclonal antibody for the detection of Human Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Potassium Voltage-Gated Channel Subfamily A Member 3 (KCNA3)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P22001
Gene ID
3738
NCBI Accession
NP_002223.3
Background
Antibody anti-KCNA3
Status
RUO

Descripción

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Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes shaker, shaw, shab, and shal have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.

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