Porcine VCAM1(Vascular cell adhesion protein 1) ELISA Kit

Este producto es parte de VCAM1 - Vascular Cell Adhesion Molecule 1
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935106861
info@markelab.com
name
Porcine VCAM1(Vascular cell adhesion protein 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EP0196

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
porcine
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich ELISA, Double Antibody
Test Range
1.563-100ng/ml
Size 1
96T
Sample Type
Busacar en las instrucciones
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 6 months
UniProt ID
Q29123
Alias
V-CAM 1,VCAM-1,INCAM-100,CD106
Background
Elisa Kits VCAM1
Status
RUO

VCAM1 is a transmembrane glycoprotein and member of the immunoglobulin superfamily that plays a key role in cell adhesion, particularly in leukocyte-endothelial interactions during inflammation VCAM1 is expressed on endothelial cells in response to pro-inflammatory cytokines such as TNF-α and IL-1β where it mediates the adhesion and transmigration of leukocytes, including monocytes and lymphocytes, into inflamed tissues VCAM1 interacts with its ligand VLA-4 (integrin α4β1) to facilitate immune cell recruitment during acute and chronic inflammatory responses VCAM1 is implicated in various diseases including atherosclerosis, where it promotes monocyte adhesion to endothelial cells and contributes to plaque formation Elevated VCAM1 levels are also associated with rheumatoid arthritis, multiple sclerosis, and other autoimmune disorders, where persistent inflammation leads to tissue damage VCAM1 serves as a biomarker for endothelial activation and vascular inflammation, making it a potential target for therapeutic interventions aimed at reducing leukocyte recruitment and chronic inflammation

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